USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: ALDOA_HUMAN USC-OGP 2-DE database:  ALDOA_HUMAN ALDOA_HUMAN General information about the entry View entry in simple text format Entry name ALDOA_HUMAN Primary accession number P04075 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Fructose-bisphosphate aldolase A; EC=4.1.2.13; AltName: Full=Lung cancer antigen NY-LU-1; AltName: Full=Muscle-type aldolase;. Gene name Name=ALDOA Synonyms=ALDA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0959: pI=7.41; Mw=39238 SPOT OGP-0960: pI=7.51; Mw=39238 SPOT OGP-0961: pI=7.62; Mw=39146 SPOT OGP-0962: pI=8.01; Mw=38871 SPOT OGP-0963: pI=7.83; Mw=38780 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1200: pI=7.15; Mw=39675 Cross-references UniProtKB/Swiss-Prot P04075; ALDOA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ALDOA_HUMAN Primary accession number P04075 Secondary accession number(s) B4DXI7 Q6FH76 Q6FI10 Q96B15 Q9BWD9 Q9UCN2 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 207) Name and origin of the protein Description RecName: Full=Fructose-bisphosphate aldolase A; EC=4.1.2.13; AltName: Full=Lung cancer antigen NY-LU-1; AltName: Full=Muscle-type aldolase; Gene name Name=ALDOA Synonyms=ALDA Encoded on Name=ALDOA; Synonyms=ALDA Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Glycogen storage disease; Glycolysis; Hereditary hemolytic anemia; Isopeptide bond; Lyase; Phosphoprotein; Polymorphism; Reference proteome; Schiff base; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M11560; AAA51690.1; -; mRNA EMBL X05236; CAA28861.1; -; mRNA EMBL X12447; CAA30979.1; -; Genomic_DNA EMBL AK301993; BAG63399.1; -; mRNA EMBL CR536528; CAG38765.1; -; mRNA EMBL CR541880; CAG46678.1; -; mRNA EMBL AC093512; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471238; EAW79933.1; -; Genomic_DNA EMBL BC000367; AAH00367.2; -; mRNA EMBL BC004333; AAH04333.1; -; mRNA EMBL BC010660; AAH10660.1; -; mRNA EMBL BC012880; AAH12880.1; -; mRNA EMBL BC013614; AAH13614.1; -; mRNA EMBL BC015888; AAH15888.1; -; mRNA EMBL BC016170; AAH16170.1; -; mRNA EMBL BC016800; AAH16800.1; -; mRNA EMBL M21190; AAA51697.1; -; mRNA CCDS CCDS10668.1; -. [P04075-1]; . CCDS CCDS58450.1; -. [P04075-2]; . PIR S14084; ADHUA; . RefSeq NP_000025.1; NM_000034.3. [P04075-1]; . RefSeq NP_001121089.1; NM_001127617.2. [P04075-1]; . RefSeq NP_001230106.1; NM_001243177.1. [P04075-2]; . RefSeq NP_908930.1; NM_184041.2. [P04075-1]; . RefSeq NP_908932.1; NM_184043.2. [P04075-1]; . RefSeq XP_011544070.1; XM_011545768.2. [P04075-1]; . UniGene Hs.513490; -; . UniGene Hs.732822; -; . PDB 1ALD; X-ray; 2.00 A; A=2-364 PDB 2ALD; X-ray; 2.10 A; A=2-364 PDB 4ALD; X-ray; 2.80 A; A=2-364 PDBsum 1ALD; -; . PDBsum 2ALD; -; . PDBsum 4ALD; -; . ProteinModelPortal P04075; -; . SMR P04075; -; . BioGrid 106728; 111; . IntAct P04075; 37; . MINT MINT-4998828; -; . STRING 9606.ENSP00000336927; -; . ChEMBL CHEMBL2106; -; . DrugBank DB08240; N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE; . iPTMnet P04075; -; . PhosphoSitePlus P04075; -; . SwissPalm P04075; -; . BioMuta ALDOA; -; . DMDM 113606; -; . DOSAC-COBS-2DPAGE P04075; -; . OGP P04075; -; . REPRODUCTION-2DPAGE IPI00465439; -; . REPRODUCTION-2DPAGE P04075; -; . SWISS-2DPAGE P04075; -; . UCD-2DPAGE P04075; -; . EPD P04075; -; . PaxDb P04075; -; . PeptideAtlas P04075; -; . PRIDE P04075; -; . TopDownProteomics P04075-1; -. [P04075-1]; . DNASU 226; -; . Ensembl ENST00000338110; ENSP00000336927; ENSG00000149925. [P04075-1]; . Ensembl ENST00000395248; ENSP00000378669; ENSG00000149925. [P04075-2]; . Ensembl ENST00000412304; ENSP00000400452; ENSG00000149925. [P04075-1]; . Ensembl ENST00000563060; ENSP00000455800; ENSG00000149925. [P04075-1]; . Ensembl ENST00000564546; ENSP00000455917; ENSG00000149925. [P04075-1]; . Ensembl ENST00000564595; ENSP00000457468; ENSG00000149925. [P04075-2]; . Ensembl ENST00000566897; ENSP00000455724; ENSG00000149925. [P04075-1]; . Ensembl ENST00000569545; ENSP00000455700; ENSG00000149925. [P04075-1]; . GeneID 226; -; . KEGG hsa:226; -; . UCSC uc010veg.3; human. [P04075-1]; . CTD 226; -; . DisGeNET 226; -; . GeneCards ALDOA; -; . HGNC HGNC:414; ALDOA; . HPA CAB006252; -; . HPA HPA004177; -; . MalaCards ALDOA; -; . MIM 103850; gene; . MIM 611881; phenotype; . neXtProt NX_P04075; -; . OpenTargets ENSG00000149925; -; . Orphanet 57; Glycogen storage disease due to aldolase A deficiency; . PharmGKB PA24707; -; . eggNOG KOG1557; Eukaryota; . eggNOG COG3588; LUCA; . GeneTree ENSGT00390000010235; -; . HOVERGEN HBG002386; -; . InParanoid P04075; -; . KO K01623; -; . OMA PNMVIDG; -; . OrthoDB EOG091G0A9T; -; . PhylomeDB P04075; -; . TreeFam TF314203; -; . BioCyc MetaCyc:HS07647-MONOMER; -; . BRENDA 4.1.2.13; 2681; . Reactome R-HSA-114608; Platelet degranulation; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-70171; Glycolysis; . Reactome R-HSA-70263; Gluconeogenesis; . SABIO-RK P04075; -; . UniPathway UPA00109; UER00183; . EvolutionaryTrace P04075; -; . GeneWiki Aldolase_A; -; . GenomeRNAi 226; -; . PRO PR:P04075; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000149925; -; . CleanEx HS_ALDOA; -; . ExpressionAtlas P04075; baseline and differential; . Genevisible P04075; HS; . GO GO:0015629; C:actin cytoskeleton; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0031674; C:I band; TAS:BHF-UCL; . GO GO:0031430; C:M band; IEA:UniProtKB-SubCell; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0031093; C:platelet alpha granule lumen; TAS:Reactome; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:1904724; C:tertiary granule lumen; TAS:Reactome; . GO GO:0003779; F:actin binding; TAS:BHF-UCL; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL; . GO GO:0070061; F:fructose binding; IDA:BHF-UCL; . GO GO:0004332; F:fructose-bisphosphate aldolase activity; IDA:BHF-UCL; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0015631; F:tubulin binding; TAS:BHF-UCL; . GO GO:0007015; P:actin filament organization; TAS:BHF-UCL; . GO GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL; . GO GO:0061621; P:canonical glycolysis; TAS:Reactome; . GO GO:0030388; P:fructose 1; 6-bisphosphate metabolic process; IDA:BHF-UCL GO GO:0006000; P:fructose metabolic process; IMP:BHF-UCL; . GO GO:0006094; P:gluconeogenesis; TAS:Reactome; . GO GO:0006096; P:glycolytic process; IMP:BHF-UCL; . GO GO:0046716; P:muscle cell cellular homeostasis; IMP:BHF-UCL; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0051289; P:protein homotetramerization; ISS:UniProtKB; . GO GO:0008360; P:regulation of cell shape; IDA:BHF-UCL; . GO GO:0006941; P:striated muscle contraction; IMP:BHF-UCL; . Gene3D 3.20.20.70; -; 1; . InterPro IPR029768; Aldolase_I_AS; . InterPro IPR013785; Aldolase_TIM; . InterPro IPR000741; FBA_I; . Pfam PF00274; Glycolytic; 1; . PROSITE PS00158; ALDOLASE_CLASS_I; 1; .

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